Preimplantation genetic screening (PGS)
In the PERSONA International Clinical Center for Reproduction, a complete genetic examination is available for couples with infertility, miscarriage, and unsuccessful IVF attempts.
Preimplantation genetic research of embryos (PGD / PGS) with full chromosomal screening by comparative genomic hybridization (aCGH)
Preimplantation genetic diagnostics by the method of genomic hybridization on microchips (aCGH) is one of the most innovative technologies in modern reproductology.
Diagnostics of CGH allows to detect chromosomal pathology with high accuracy (up to 98%) on all 23 pairs of chromosomes before embryo transfer in ART cycles (assisted reproductive technologies). The method increases the success of the IVF procedure up to 60-70%, instead of the usual 30-40%. A more “old” method of genetic diagnosis of embryos - FISH allows you to check only 3 to 9 pairs of chromosomes, i.e. most of the chromosomes remained untested.
Why it is important to conduct a preimplantation genetic study of embryos (PGD / PGS) with full chromosomal screening using the comparative genomic hybridization (aCGH) method:
The method of comparative genomic hybridization should be carried out in the case of:
- If the history of the disease already has one or several "missed" pregnancies
- two or more failed IVF attempts
- Age of mother over 37 years old
- severe male infertility
- If the patient has already been diagnosed with a pregnancy with a chromosomal abnormality, or the couple already have one child with a chromosomal abnormality;
- One or both parents are carriers of balanced structural chromosomal abnormalities